SRA

The goals of this study are to compare different gene expressions for Penicillium oxalicum wild type strain (WT) and FaiR deletion strain (DfaiR) under conditions of 1% bran + 1% microcrystalline cellulose as carbon source. The results of correlation analysis between each sample showed that the gene expression level of DfaiR was significantly different from that of the WT strain. The deletion of DfaiR significantly down-regulates the expression levels of sporulation process genes. And the absence of DfaiR can broadly up-regulate the expression level of cellulase-encoding genes, indicating that DfaiR can cause a decrease in cellulase synthesis by affecting the expression of cellulase-encoding genes. Overall design: Examination of differential gene expressions by digital gene expression tag profiling in Penicillium oxalicum wild type strain, faiR deletion mutant strain in 18h in modified Mendal's medium with 1% bran + 1% microcrystalline cellulose as carbon sources. Three replicates were included for each samples.